David de Gea: Having recovered from a finger injury to play in Rio Ferdinand’s testimonial, De Gea is ready to start against Wigan.
Rafael: One of United’s best performers last season, Rafael will be looking to recreate that form in the year ahead.
Nemanja Vidic: Having recovered from injury, United’s captain will probably lead the team out on Sunday.
Phil Jones: Jones has had a good workout in pre-season and could partner Vidic at Wembley.
Patrice Evra: Evra was rested against Sevilla in Ferdinand’s testimonial with a view to starting this game against Wigan.
Wilfried Zaha: The young starlet may be rewarded with a start against Wigan after an encouraging pre-season.
Michael Carrick: Carrick is set to remain one of the top-class stalwarts in United’s starting eleven this season.
Anderson: The Brazilian has been used often in pre-season and is therefore a favourite to partner Carrick on Sunday.
Ashley Young: Being in a rare spell of full fitness, Young could be one of Moyes’ wingers against Wigan.
Danny Welbeck: The Englishman has played well on United’s pre-season and will be looking to take that into the year ahead.
Robin van Persie: United’s first-choice striker is almost certain to start.
In David Moyes’ first competitive game as manager of Manchester United, his team selection could be an indicator of his favoured starting XI for the rest of the season.
Danny Welbeck may well be chosen to partner Robin van Persie in the final third but it would be no surprise to see Shinji Kagawa or Ryan Giggs involved in such a role either. Antonio Valencia and Tom Cleverley can also expect some sort of involvement on Sunday.